London Buses route 621 is a Transport for London contracted bus route in London, England. Running between Lewisham and Crown Woods School, it is operated by Stagecoach London.
On 14 October 2017, the route was retained by Stagecoach London.
- Lewisham Station Molesworth Street
- Lee Green
- Eltham Green
- Eltham Park
- Avery Hill Crown Woods School